The 2000 NIH evaluation concluded that condom use substantially lowers the threat of gonorrhea for males. According to a 2000 report by the National Institutes of Health (NIH), consistent use of latex condoms lessens the danger of HIV transmission by around 85% relative to danger when unprotected, putting the seroconversion amount (an infection fee) at .9 per one hundred individual-many years with condom, down from 6.