Searle company. He was functioning on an anti-ulcer drug and unintentionally spilled some aspartame on his hand. In the United States, the Food and Drug Administration banned the sale of cyclamate in 1969 immediately after lab tests in rats involving a 10:1 combination of cyclamate and saccharin (at degrees equivalent to humans ingesting 550 cans of diet program soda for each working day) brought on bladder most cancers.