The enzyme cytochrome P450 (CYP1B1) has been implicated in cancer advancement and progression. In this research, the outcomes of PA, EA, POMx, and PJ on the expression of androgen-synthesizing enzyme genes and the androgen receptor were also measured. 5. Yuan T, Ma H, Liu W, et al.: Pomegranate's Neuroprotective Outcomes against Alzheimer's Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites. 15.